Recent  Publications
  • Yanovich C, Kirby M, Michaelevski I, Yadid G, Pinhasov A Critical role of personality in stress-induced drug dependency. Scientific Reports 2018 (Accepted SREP-17-42744A)

  • Borovok N, Nesher E, Reichenstein M, Levin Y, Tikhonova T, Pinhasov A and Michaelevski I.& Hippocampal protein expression alteration in depression mice models in naïve vs. stress conditions Molecular and cellular proteomics. Proteomics Clin Appl. 2017 Jul 5. doi: 10.1002/prca.201700089.

  • Singer-Lahat D, Barak-Broner N, Sheinin A, Gretzer-Antes D, Michaelevski I and Lotan I The dual function of the polybasic juxtamembrane region of syntaxin 1A in clamping spontaneous release and stimulating Ca2+-triggered neurotransmitter release in neuroendocrine cells. J Neuroscience 2018 Jan 3;38(1):220-231. doi: 10.1523/JNEUROSCI.1541-17.2017

  • Ganz J, Cohen-Matsliah SI, Shor E, Sheinin A, Arie I, Michaelevski I, Pitaru S, Offen D and Levenberg S. Implantation of 3-D constructs embedded with oral mucosa-derived cells induces functional recovery in rats with complete spinal cord transection. Frontiers in Neuroscience 2017 Oct 31;11:589. doi: 10.3389/fnins.2017.00589

  • Pen Y, Borovok N, Sheinin A, Reichenstein M, Michaelevski I The role of membrane anchored AKT in regulation of basic synaptic transmission and early phase LTP expression.  Hippocampus 2016; Sep;26(9):1149-67.; doi: 10.1002/hipo.22597; PMID: 27068236

  • Chandran V, Coppola G, Omura T, Nawabi H, Versano R, Costigan M, Blesch A, Michaelevski I, Davis-Turak J, Gao F, Langfelder P, Horvath S, He Z, Fainzilber M, Tuszynski M, Woolf C J, Geschwind D, A  Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron. 2016 Mar 2;89(5):956-70. doi: 10.1016/j.neuron.2016.01.034.

  • Borovok N, Nesher E, Levin Y, Reichenstein M,  Pinhasov A, Michaelevski I&, Time dependent protein expression alteration occurring in hippocampus during in formation of long-term spatial memory.  Molecular and cellular proteomics (accepted in MCP; PubMed reference:; pii: mcp.M115.051318.

  • Nesher E, Koman, I, Gross M, Tikhonov T, Bairachnaya M, Gerliz G, Michaelevski I, Yadid G, Pinhasov A.  Synapsin IIb as a functional marker of submissive behavior Scientific Reports 2015 May 22; 5:10287. doi: 10.1038/srep10287.

  • Gross M, Sheinin A, Nesher E, Tikhonov T, Baranes D, Pinhasov,A, Michaelevski I& Early onset of cognitive impairment is associated with altered synaptic plasticity and enhanced hippocampal GluA1 expression in a mouse model of depression Neurobiology of aging. 2015 May;36(5):1938-52. doi: 10.1016/j.neurobiolaging.2015.02.015.

  • Sheinin A, Lavi A, Michaelevski I&.  StimDuino: an Arduino-based electrophysiological stimulus isolator.  Journal of Neuroscience methods. 2015 Mar 30; 243:8-17. doi: 10.1016/j.jneumeth.2015.01.016.

  • Cho Y, Liberto V D, Carlin D, Abe N, Burlingame A L, Li K H , Guan S, Michaelevski I, and Cavalli V, The   SNARE protein syntaxin13 is an mTOR translational target promoting axon regeneration.  J Biol Chem. 2014 May 30;289 (22):15820-32

  • Moscovitz O, Tsvetkov P, Hazan N, Michaelevski I, Keisar H, Ben-Nissan G, Shaul Y, Sharon M. A. Molecular Cell 2012 Jul 13; 47(1):76-86.

Manuscripts Submitted or on Revision 
  • Reichenstein M, Sheinin A, Borovok N, Michaelevski I&.  Abl Kinase mediates spontaneous synaptic activity depression induced by Amyloid Beta 1-42 peptides (Scientific Reports, pending on revision).

  • Panayotis N, Dagan S, Sheinin A, Rother F, Hartmann E, Bader M, Michaelevski I, Fainzilber M#. Deciphering Importin-a Roles in Mammalian Central Neurons. Neuron (pending on revision)

Previous Publications
  • Michaelevski I, Lotan I. Role of neuronal potassium M-channels in sympathetic regulation of cardiac function. J Physiol. 2011 Jun 1; 589(Pt 11):2659-60

  • Michaelevski I Segal-Ruder Y, Rozenbaum M, Medzihradszky K.F, Shalem O, Coppola G, Horn-Saban S, Ben-Yaakov K, Dagan S.Y, Rishal I, Geshwind D.H, Pilpel Y, Burlingame A.L, & Fainzilber M. Signaling to Transcription Networks in the Neuronal Retrograde Injury response. Science Signaling. 2010 Jun 13; 3(130):ra53

  • Michaelevski I&, Medzihradszky KF, Burlingame,AL & Fainzilber M&: Axonal transport proteomics reveals mobilization translation machinery to the lesion site in injured sciatic nerve. Mol. Cell. Proteomics. 2010 May 9(5):976-87

  • Michaelevski I, Eisenstein M, Sharon M: Gas-phase compaction and unfolding of protein structures. Analytical Chemistry 2010, Nov 15;82(22):9484-91

  • Lvov A, Greitzer D, Chikvashvili D, Tsuk S, Berlin S, Lotan I& and Michaelevski I& Rearrangement in the relative orientation of cytoplasmic domains induced by a membrane anchored protein – mediated Kv channel gating modulation. J Biol Chem 2009, 284(41):28276-91

  • Rishal I, Michaelevski I, Shinder V, Medzihradszky K.F, Burlingame A.L, & Fainzilber M Axoplasm Isolation from Peripheral Nerve. Developmental Neurobiology, 2010 Feb; 70(2):126-33

  • Kirshenbaum N, Michaelevski I, Sharon M. Analyzing Large Protein Complexes by Structural Mass Spectrometry. Journal of Visualized Experiments, 2010; ePublish: Details.stp?ID=1954; Review

  • Michaelevski I, Kirshenbaum N, Sharon M. T-wave Ion Mobility-mass Spectrometry: Basic Experimental Procedures for Protein Complex Analysis. Journal of Visualized Experiments, 2010; ePublish:; Review

  • Feinshreiber L, Chikvashvili D, Michaelevski I, Lotan I. Syntaxin modulates Kv1.1 through dual action on channel surface expression and conductance. Biochemistry. 2009 May 19;48(19):4109-14

  • Tsuk S, Lvov A, Michaelevski I, Chikvashvili D, Lotan I. Formation of the full SNARE complex eliminates interactions of its individual protein components with the Kv2.1 channel. Biochemistry. 2008 Aug 12;47(32):8342-9

  • Lvov A, Chikvashvili D, Michaelevski I, Lotan I. VAMP2 interacts directly with the N terminus of Kv2.1 to enhance channel inactivation. Pflugers Arch. 2008 Sep; 456(6):1121-36

  • Michaelevski I, Korngreen A, Lotan I. Interaction of syntaxin with a single Kv1.1 channel: a possible mechanism for modulating neuronal excitability. Pflugers Arch. 2007 Jun;454(3):477-94

  • Perlson E, Michaelevski I, Kowalsman N, Ben-Yaakov K, Shaked M, Seger R, Eisenstein M, Fainzilber M. Vimentin binding to phosphorylated erk sterically hinders enzymatic dephosphorylation of the kinase.J Mol Biol. 2006 Dec 15;364(5):938-44

  • Wolf-Goldberg T*, Michaelevski I*, Sheu L, Gaisano HY, Chikvashvili D, Lotan I Target soluble N- ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels. Mol Pharmacol. 2006 Sep;70(3):818-28

  • Tsuk S*, Michaelevski I*, Bentley GN, Joho RH, Chikvashvili D, Lotan I Kv2.1 channel activation and inactivation is influenced by physical interactions of both syntaxin 1A and the t-SNARE complex with the C-terminus of the channel. Mol Pharmacol. 2005 Feb; 67(2): 480-8

  • Michaelevski I, Chikvashvili D, Tsuk S, Singer-Lahat D, Kang Y, Linial M, Gaisano HY, Fili O, Lotan I. Direct interaction of target SNAREs with the Kv2.1 channel. Modal regulation of channel activation and inactivation gating. J Biol Chem. 2003 Sep 5;278(36):34320-30

  • Michaelevski I, Chikvashvili D, Tsuk S, Fili O, Lohse MJ, Singer-Lahat D, Lotan I. Modulation of a brain voltage-gated K channel by syntaxin 1A requires the physical interaction of G beta/gamma with the channel. J Biol Chem 2002 Sep 20;277(38):34909-17

  • Fili O*, Michaelevski I*, Bledi Y, Chikvashvili D, Singer-Lahat D, Boshwitz H, Linial M, Lotan I. Direct interaction of a brain voltage-gated K+ channel with syntaxin 1A: functional impact on channel gating. J Neurosci 2001 Mar 15; 21(6):1964-74

Book Chapters
  • Michaelevski I, and Fainzilber M. 2007: Proteomic approaches to axon injury–Post- genomic approaches to a posttranscriptional process. IN: Neural Degeneration and Repair–Gene Expression Profiling, Proteomics, Glycomics and Systems Biology. Editor Werner-Mueller H. 2008 Wiley-VCH Verlag GmbH &Co. KGaA

  • Pinhasov A, Michaelevski I, Koman I, Nesher E PACAP and Depression. IN: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP. Editor Dora Reglodi and Andrea Tamas. In Press.